RESPIRATORY CHAIN ENZYMES

Because the 13 proteins encoded by mtDNA are all components of respiratory chain complexes, any deleterious mutation or severe depletion of mtDNA results in impaired function of this vital terminal pathway of mitochondrial metabolism, with decreased ATP generation, excessive production of reactive oxygen radicals (ROS), or both situations.

Specimen:

Biopsy should be snap frozen immediately in liquid nitrogen and shipped on dry ice. The biopsy should be approximately 0.1 cm in diameter and 0.5 cm in length; approximate weight should be 100-200 mg.

Shipping:

Muscle: should be sent frozen on dry ice and by overnight carrier to the address below.

Dr. S. DiMauro/ Dr. S. Shanske

Columbia University Medical Center
Russ Berrie Medical Science Pavilion
1150 Saint Nicholas Avenue, Room 315
New York NY 10032
Phone: 212-305-3947
FAX: 212-305-3986

Forms:

Click here to download Respiratory Chain Enzymes PDF form.

CPT Codes:

82657 times 6, and 83912

Price:

$550.00 6-enzyme battery